Single and Mitochondrial Gene Inheritance Disorder Prediction Using Machine Learning

نویسندگان

چکیده

One of the most difficult jobs in post-genomic age is identifying a genetic disease from massive amount data. Furthermore, complicated has very diverse genotype, making it challenging to find markers. This process since must be completed effectively and efficiently. research article focuses largely on which patients are more likely have disorder based numerous medical parameters. Using patient’s history, we used prediction algorithm that predicts if patient diagnosed with disorder. To predict categorize disease, utilize several deep machine learning techniques such as Artificial neural network (ANN), K-nearest neighbors (KNN), Support vector (SVM). enhance accuracy predicting any patient, highly efficient approach was utilized control how model can used. approaches performed. The productive tool provides precise efficiency. simulation results demonstrate by using proposed ANN, achieve highest performance 85.7%, 84.9%, 84.3% training, testing validation respectively. will undoubtedly transform give real competitive strategy save patients’ lives.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Stock Price Prediction using Machine Learning and Swarm Intelligence

Background and Objectives: Stock price prediction has become one of the interesting and also challenging topics for researchers in the past few years. Due to the non-linear nature of the time-series data of the stock prices, mathematical modeling approaches usually fail to yield acceptable results. Therefore, machine learning methods can be a promising solution to this problem. Methods: In this...

متن کامل

Gene Prediction Using Machine Learning Techniques

The basic purpose of the research work aims at predicting the genes of interest in molecular sequence databases using machine learning techniques like neural networks, decision trees, data mining, hidden markov models etc The primary focus of the research will be on proposing new or improving already existing ab initio and homology based methods for gene prediction. The proposed methods will be...

متن کامل

Oral Cancer Prediction Using Gene Expression Profiling and Machine Learning

Oral premalignant lesion (OPL) patients have a high risk of developing oral cancer. In this study we investigate using machine learning techniques with gene expression profiling to predict the possibility of oral cancer development in OPL patients. Four classification techniques were used: support vector machine (SVM), Regularized Least Squares (RLS), multi-layer perceptron (MLP) with back prop...

متن کامل

Gene Ontology (GO) Prediction using Machine Learning Methods

We applied machine learning to predict whether a gene is involved in axon regeneration. We extracted 31 features from different databases and trained five machine learning models. Our optimal model, a Random Forest Classifier with 50 submodels, yielded a test score of 85.71%, which is 4.1% higher than the baseline score. We concluded that our models have some predictive capability. Similar meth...

متن کامل

Mitochondrial DNA Mutations, Pathogenicity and Inheritance

Mitochondria contain their own DNA (mtDNA), which codes for 13 proteins (all subunits of the respiratory chain complexes), 22 tRNAs and 2 rRNAs. Several mtDNA point mutations as well as deletions have been shown to be causative in well-defined mitochondrial disorders. A mixture of mutated and wild type mtDNA (heteroplasmy) is found in most of these disorders. Inheritance of mtDNA is maternal, a...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Computers, materials & continua

سال: 2022

ISSN: ['1546-2218', '1546-2226']

DOI: https://doi.org/10.32604/cmc.2022.028958